Cryoprecipitate is used to replace which factors?

Cryoprecipitate is used to replace which factors?

• A. Factor VIII and von Willebrand factor
• B. Fibrinogen, Factor VIII, von Willebrand factor, Factor XIII
• C. Factor IX, Factor VII
• D. Platelets

Answer: (B)

Cryoprecipitate is a plasma-derived product rich in fibrinogen, Factor VIII, Factor XIII, and von Willebrand factor. It is used to replace those specific components when they are deficient, such as low fibrinogen levels, Factor VIII needs in certain contexts, Factor XIII deficiency, or von Willebrand factor-related issues. This makes it the best choice because it directly supplies all four factors known to be concentrated in cryoprecipitate. It does not primarily provide platelets, so platelet transfusion is the wrong approach for replacing platelets. It also does not reliably supply Factor IX or Factor VII in amounts used for targeted reversal or replacement, which is why options emphasizing those factors are not appropriate.

Cryoprecipitate is a plasma-derived product rich in fibrinogen, Factor VIII, Factor XIII, and von Willebrand factor. It is used to replace those specific components when they are deficient, such as low fibrinogen levels, Factor VIII needs in certain contexts, Factor XIII deficiency, or von Willebrand factor-related issues. This makes it the best choice because it directly supplies all four factors known to be concentrated in cryoprecipitate.

It does not primarily provide platelets, so platelet transfusion is the wrong approach for replacing platelets. It also does not reliably supply Factor IX or Factor VII in amounts used for targeted reversal or replacement, which is why options emphasizing those factors are not appropriate.